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Document ID (ISN)110806
CIS number 10-0383
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2010
Convention or series no.
Author(s) Rui F., Bovenzi M., Prodi A., Belloni Fortina A., Romano I., Peserico A.,, Corradin M.T., Carrabba E., Larese Filon F.
Title Nickel, cobalt and chromate sensitization and occupation
Bibliographic information Apr. 2010, Vol.62, No.4, p.225-231. 39 ref.
Abstract Exposure to nickel, cobalt and chromate are important causes of occupational contact dermatitis. The aim of this study was to estimate the prevalence of nickel, cobalt and chromate allergy in a population of consecutive patients of an occupational health clinic in Italy, and to investigate the possible association with individual and occupational risk factors. A total of 14,464 patients (67.6% women and 32.4% men) with suspected allergic dermatitis underwent patch tests. The associations between patch test results and occupations were studied by multivariate logistic regression analysis. Positive reactions to nickel sulfate were observed in 24.6% of the patients, while 10.2% reacted positively to cobalt chloride and 8.7% to potassium dichromate. Nickel sensitization was higher in women aged 26-35 years in comparison with the youngest group (15-25 years) and the older group (> 45 years). In women, the prevalence of positive reactions to nickel was positively associated with metal and mechanical work. Chromate sensitization was more prevalent in building trade workers for both women and men. Cobalt sensitization was associated with textile and leather work in women.
Descriptors (primary) chromates; cobalt and compounds; nickel and compounds; sensitization; eczema
Descriptors (secondary) Italy; nickel sulfate; potassium dichromate; occupational diseases; skin tests; statistical evaluation; women; age-linked differences
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Statistical methods
Nickel and compounds
Women