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Document ID (ISN)110794
CIS number 10-0344
ISSN - Serial title 0019-8366 - Industrial Health
Year 2010
Convention or series no.
Author(s) Heo Y., Lee S.H., Kim S.H., Lee S.H., Kim H.A.
Title Public facility workers' immunological characteristics involved with development of respiratory allergic diseases in Korea
Bibliographic information Mar. 2010, Vol.48, No.2, p.171-177. 32 ref.
Internet access Public_facility_workers.pdf [in English]
Abstract The immuno-pulmonary status of employees working at public facilities was evaluated to determine whether they are at greater risk of developing respiratory allergies. Fifty-two employees from child daycare centres, elderly nursing homes, subway stations and hypermarkets, and 17 office workers were recruited. All were subjected to a skin prick test (SPT) for 25 aeroallergens and the methacholine bronchial challenge test. Various immunological parameters, including plasma IgE and IgG4 levels, hematology parameters and in vitro cytokine production from peripheral T cells, were assessed. Forced vital capacity (FVC) and one-second forced expiratory volume (FEV1) were also determined. Of the facility employees, 54% responded to the SPT, and house dust mite induced positive skin reactions most frequently. Compared to the SPT-negative facility employees and the office workers, the SPT-positive facility employees had upregulated plasma IgE levels and eosinophil frequency in their peripheral blood. Findings are discussed. This study suggests that workers at public facilities could show greater risk towards the development of respiratory allergic diseases.
Descriptors (primary) Korea, Republic of; allergic respiratory disorders; pulmonary function; immunology; community services
Descriptors (secondary) respirable dust; immunoglobulins; skin tests; respiratory function tests; comparative study; hypersensitivity
Document type D - Periodical articles
Subject(s) Commerce, services, offices
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Allergies