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Document ID (ISN)110449
CIS number 10-0084
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2010
Convention or series no.
Author(s) Vander Hulst K., Kerre S., Goossens A.
Title Occupational allergic contact dermatitis from tetrazepam in nurses
Bibliographic information May 2010, Vol.62, No.5, p.303-308. Illus. 21 ref.
Abstract Tetrazepam is a muscle relaxant belonging to the benzodiazepine group. Drug eruptions following ingestion of tetrazepam tablets are well known. The objective of this study was to draw the attention to occupational airborne dermatitis and/or hand dermatitis among nurses involved in crushing of tablets for elderly or disabled people. Since 2003, 16 nurses with facial (eyelid) and/or hand dermatitis, suspected to be of occupational origin, were patch tested in the dermatology department of a Belgian hospital with the medication they handled during work. Ten nurses presented with a positive patch test reaction to tablets containing tetrazepam, 14 controls remaining negative. Some of them also reacted to other drugs. Implications of these findings are discussed.
Descriptors (primary) benzodiazepines; allergens; skin allergies; nursing personnel
Descriptors (secondary) Belgium; airborne dust; hand; skin tests; case study
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Health care services