|Document ID (ISN)||110403|
|ISSN - Serial title
||0019-8366 - Industrial Health
|Convention or series no.
||Dai Y., Leng S., Li L., Niu Y., Huang H., Liu Q., Duan H., Cheng J., Zheng Y.
||Effects of genetic polymorphisms of N-acetyltransferase on trichloroethylene-induced hypersensitivity dermatitis among exposed workers
||Sep. 2009, Vol.47, No.5, p.479-486. 41 ref.
||http://www.jniosh.go.jp/en/indu_hel/pdf/IH_47_5_479.pdf [in English]
||This case-control study was conducted to investigate effects of various genotypes and phenotypes of N-acetyltransferases (NATs) on individual susceptibility to trichloroethylene (TCE)-induced hypersensitivity dermatitis. The study involved 111 patients with hypersensitivity dermatitis and 154 healthy TCE-exposed workers. Polymerase chain reaction-restriction fragment length polymorphism was used to detect the polymorphic sites of NATs. Data were subjected to logistic regression analyses. Findings are discussed.
||sensitization dermatitis; individual susceptibility; trichloroethylene
||DNA; transferases; statistical evaluation; genetic effects; case-control study
||D - Periodical articles
|Country / State or Province||China|
|Broad subject area(s)
||Occupational medicine, epidemiology
Genetic factors in reaction to exposures