| Document ID (ISN) | 110403 |
| CIS number |
09-1228 |
| ISSN - Serial title |
0019-8366 - Industrial Health |
| Year |
2009 |
| Convention or series no. |
|
| Author(s) |
Dai Y., Leng S., Li L., Niu Y., Huang H., Liu Q., Duan H., Cheng J., Zheng Y. |
| Title |
Effects of genetic polymorphisms of N-acetyltransferase on trichloroethylene-induced hypersensitivity dermatitis among exposed workers |
| Bibliographic information |
Sep. 2009, Vol.47, No.5, p.479-486. 41 ref. |
| Internet access |
http://www.jniosh.go.jp/en/indu_hel/pdf/IH_47_5_479.pdf [in English]
|
| Abstract |
This case-control study was conducted to investigate effects of various genotypes and phenotypes of N-acetyltransferases (NATs) on individual susceptibility to trichloroethylene (TCE)-induced hypersensitivity dermatitis. The study involved 111 patients with hypersensitivity dermatitis and 154 healthy TCE-exposed workers. Polymerase chain reaction-restriction fragment length polymorphism was used to detect the polymorphic sites of NATs. Data were subjected to logistic regression analyses. Findings are discussed. |
| Descriptors (primary) |
sensitization dermatitis; individual susceptibility; trichloroethylene |
| Descriptors (secondary) |
DNA; transferases; statistical evaluation; genetic effects; case-control study |
| Document type |
D - Periodical articles |
| Country / State or Province | China |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Occupational medicine, epidemiology
|
| Browse category(ies) |
Halogenated hydrocarbons
Genetic factors in reaction to exposures
Skin diseases
|
