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CISDOC database

Document ID (ISN)110273
CIS number 09-1246
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2008
Convention or series no.
Author(s) Stayner L., Kuempel E., Gilbert S., Hein M., Dement J.
Title An epidemiological study of the role of chrysotile asbestos fibre dimensions in determining respiratory disease risk in exposed workers
Bibliographic information Sep. 2008, Vol.65, No.9, p.613-619. Illus. 25 ref.
Abstract The relation between cumulative exposure to asbestos, pathological grade of pulmonary fibrosis, and lung burden of asbestos at death was explored in a deceased population of former workers in an asbestos textile plant in South Carolina. Estimates of cumulative, mean, and peak exposures were available for 54 workers. Autopsy records and lung tissue samples were obtained from hospital files. Cumulative exposures to asbestos and lung fibre burdens were both found to be strongly correlated with the severity of asbestosis. The data also supported the hypothesis that the high prevalence of asbestosis and lung cancer in this population resulted from exposure to long fibres of chrysotile.
Descriptors (primary) asbestos processing industry; textile industry; respiratory diseases; South Carolina
Descriptors (secondary) x-ray spectrometry; USA; asbestos; chrysotile; pulmonary fibrosis; dose-response relationship; exposure evaluation; histopathology; autopsy; electron microscopy; mineral fibres
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Woodworking industry
Textile and clothing industries
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)