|Document ID (ISN)||110269|
|ISSN - Serial title
||0340-0131 - International Archives of Occupational and Environmental Health
|Convention or series no.
||Taeger D., Johnen G., Wiethege T., Tapio S., Möhner M., Wesch H., Tannapfel A., Müller K.M., Brüning T., Pesch B.
||Major histopathological patterns of lung cancer related to arsenic exposure in German uranium miners
||July 2009, Vol.82, No.7, p.867-875. Illus. 45 ref.
||A comprehensive histopathological database and a detailed job-exposure matrix developed for former German uranium miners with exposure to arsenic, radon, and quartz were analyzed to quantitatively assess the effect of arsenic regarding cell type of lung cancer. An arsenic-related increase of the proportion of squamous cell carcinoma of the lung was observed, but was restricted to miners without silicosis. The increase was found at all levels of co-exposure to radon and quartz dust. In miners with silicosis, the proportion of adenocarcinoma increased with rising arsenic exposure. Other findings are discussed.
||Germany; uranium mining; histopathology; lung cancer
||radon; arsenic and compounds; quartz; computerized data bases; confounding factors; job-exposure relation; silicosis
||D - Periodical articles
|Country / State or Province||Germany|
||Mines and quarries
|Broad subject area(s)
Occupational medicine, epidemiology
||Diseases of the respiratory system (except for pneumoconiosis & similar)
Mining and quarrying