|Document ID (ISN)||110237|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||d'Errico A., Pasian S., Baratti A., Zanelli R., Alfonzo S., Gilardi L., Beatrice F., Bena A., Costa G.
||A case-control study on occupational risk factors for sino-nasal cancer
||July 2009, Vol.66, No.7, p.448-455. 40 ref.
||The aim of this study was to investigate the risk factors of sinonasal epithelial cancer, with emphasis on metalworking industries. Between 1996 and 2000, incident cases were collected from cancer registry of the Piedmont region of Italy. A questionnaire on occupational history, completed by 113 cases and 336 hospital controls, was used to assign exposure to occupational hazards. Data were subjected to unconditional logistic regression analyses. The risk of adenocarcinoma was significantly related to exposure to wood dust (odds ratio OR 58.6), leather dust (OR 32.8) and organic solvents (OR 4.3), while ever-exposure to welding fumes (OR 3.7) and arsenic (OR 4.4) significantly increased the risk for squamous cell carcinoma. For each of these hazards, significant dose-response relationships were found. Other findings are discussed.
||Piedmont; risk factors; metalworking industry; nasal cancer
||wood dust; leather; Italy; arsenic; carcinoma; statistical evaluation; welding fumes; exposure evaluation; questionnaire survey; case-control study; dose-response relationship; organic solvents
||D - Periodical articles
|Country / State or Province||Italy|
|Broad subject area(s)
||Occupational medicine, epidemiology
Diseases of the respiratory system (except for pneumoconiosis & similar)