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Document ID (ISN)110237
CIS number 09-1218
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2009
Convention or series no.
Author(s) d'Errico A., Pasian S., Baratti A., Zanelli R., Alfonzo S., Gilardi L., Beatrice F., Bena A., Costa G.
Title A case-control study on occupational risk factors for sino-nasal cancer
Bibliographic information July 2009, Vol.66, No.7, p.448-455. 40 ref.
Abstract The aim of this study was to investigate the risk factors of sinonasal epithelial cancer, with emphasis on metalworking industries. Between 1996 and 2000, incident cases were collected from cancer registry of the Piedmont region of Italy. A questionnaire on occupational history, completed by 113 cases and 336 hospital controls, was used to assign exposure to occupational hazards. Data were subjected to unconditional logistic regression analyses. The risk of adenocarcinoma was significantly related to exposure to wood dust (odds ratio OR 58.6), leather dust (OR 32.8) and organic solvents (OR 4.3), while ever-exposure to welding fumes (OR 3.7) and arsenic (OR 4.4) significantly increased the risk for squamous cell carcinoma. For each of these hazards, significant dose-response relationships were found. Other findings are discussed.
Descriptors (primary) Piedmont; risk factors; metalworking industry; nasal cancer
Descriptors (secondary) wood dust; leather; Italy; arsenic; carcinoma; statistical evaluation; welding fumes; exposure evaluation; questionnaire survey; case-control study; dose-response relationship; organic solvents
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Metalworking industry
Diseases of the respiratory system (except for pneumoconiosis & similar)