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Document ID (ISN)110023
CIS number 09-1035
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2008
Convention or series no.
Author(s) Mirabelli D., Calisti R., Barone-Adesi F., Fornero E., Merletti F., Magnani C.
Title Excess of mesotheliomas after exposure to chrysotile in Balangero, Italy
Bibliographic information Dec. 2008, Vol.65, No.12, p.815-819. 21 ref.
Abstract Chrysotile from the mine in Balangero, Italy, is considered to be free of tremolite. In an earlier cohort study of miners and millers working on this site, only two pleural cancers were reported, suggesting that chrysotile has a low potency for inducing mesothelioma. However, follow-up ended in 1987. To complete the assessment, this study searched the regional cancer registry for cases of pleural mesothelioma among employees of the mine, employees of subcontractors and individuals exposed to mine tailings. Four new cases of pleural mesothelioma were identified among blue-collar workers in the mine, in addition to the two reported in the earlier cohort study. Thus, six mesotheliomas occurred, compared to the 1.5 expected. A further 14 mesothelioma cases occurred among other site workers and 13 among other persons exposed to chrysotile, providing further evidence that even tremolite-free chrysotile is carcinogenic.
Descriptors (primary) Italy; asbestos; mining and quarrying; pleural mesothelioma; risk factors; chrysotile
Descriptors (secondary) case study; tremolite; long-term study; subcontractors; health service records; blue-collar workers; carcinogenic effects
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Mines and quarries
Broad subject area(s) Occupational medicine, epidemiology
Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Asbestos
Mining and quarrying