Document ID (ISN) | 109995 |
CIS number |
09-795 |
ISSN - Serial title |
1059-924X - Journal of Agromedicine |
Year |
2009 |
Convention or series no. |
|
Author(s) |
Chiu B.C., Blair A. |
Title |
Pesticides, chromosomal aberrations, and non-Hodgkin's lymphoma |
Bibliographic information |
2nd Quarter 2009, Vol.14, No.2, p.250-255. 20 ref. |
Abstract |
An excessive incidence of non-Hodgkin's lymphoma (NHL) has been reported among farmers and other occupational groups working with pesticides. Some pesticides exhibit immunotoxic and genotoxic activities. Individuals exposed to pesticides have also been found to have an increased prevalence of chromosomal abnormalities. Two recent epidemiologic studies reported that the association between pesticide exposures and risk of NHL was largely limited to NHL cases with the chromosomal translocation t(14;18). This review summarizes the findings of various epidemiologic studies, speculates on implications, and suggests the research needed to clarify the role of pesticides in NHL. |
Descriptors (primary) |
lymphoma; pesticides; agriculture; risk factors; chromosome changes |
Descriptors (secondary) |
literature survey; epidemiology; immunotoxic effects; research; exposure evaluation |
Document type |
D - Periodical articles |
Country / State or Province | USA |
Subject(s) |
Agriculture, fishing, animal husbandry Toxic and dangerous substances
|
Broad subject area(s) |
Chemical safety Occupational medicine, epidemiology
|
Browse category(ies) |
Agricultural chemicals Agriculture Genetic factors in reaction to exposures Antifertility and prenatal effects Blood diseases
|