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Document ID (ISN)109995
CIS number 09-795
ISSN - Serial title 1059-924X - Journal of Agromedicine
Year 2009
Convention or series no.
Author(s) Chiu B.C., Blair A.
Title Pesticides, chromosomal aberrations, and non-Hodgkin's lymphoma
Bibliographic information 2nd Quarter 2009, Vol.14, No.2, p.250-255. 20 ref.
Abstract An excessive incidence of non-Hodgkin's lymphoma (NHL) has been reported among farmers and other occupational groups working with pesticides. Some pesticides exhibit immunotoxic and genotoxic activities. Individuals exposed to pesticides have also been found to have an increased prevalence of chromosomal abnormalities. Two recent epidemiologic studies reported that the association between pesticide exposures and risk of NHL was largely limited to NHL cases with the chromosomal translocation t(14;18). This review summarizes the findings of various epidemiologic studies, speculates on implications, and suggests the research needed to clarify the role of pesticides in NHL.
Descriptors (primary) lymphoma; pesticides; agriculture; risk factors; chromosome changes
Descriptors (secondary) literature survey; epidemiology; immunotoxic effects; research; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Agriculture, fishing, animal husbandry
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Blood diseases
Antifertility and prenatal effects
Agriculture
Agricultural chemicals
Genetic factors in reaction to exposures