ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)109556
CIS number 09-640
ISSN - Serial title 0019-8366 - Industrial Health
Year 2008
Convention or series no.
Author(s) Loh C.H., Liou S.H., Jiau S.S., Cheng W.T., Shih T.S., Chen H.I.
Title Hepatic effects among workers exposed to ethylene glycol monoethyl ether acetate
Bibliographic information Sep. 2008, Vol.46, No.5, p.463-469. 33 ref.
Internet access http://www.jniosh.go.jp/en/indu_hel/pdf/IH_46_5_463.pdf [in English]
Abstract The objective of this case-control study was to determine whether ethylene glycol monoethyl ether acetate (EGEEA) was a hepatotoxin in exposed workers. A total of 29 workers from a silk-screening shop, using EGEEA as the major cleaning solvent, were recruited as high exposure group, while a group of 57 workers with indirect and low exposure to EGEEA were selected as the comparison group. Air concentrations of EGEEA were measured by 8-h personal sampling. The mean of air EGEEA concentration in the high and low exposure groups was 7.41-16.5 ppm and 0.07-3.62 ppm respectively. Liver function profiles in both male and female EGEEA-exposed workers were not significantly different from those in the comparison group. Furthermore, no significant change in hepatic function was noted after a two-year follow-up study of these EGEEA-exposed workers. These findings suggest that EGEEA is not a hepatotoxin in this workplace.
Descriptors (primary) hepatotoxic effects; Taiwan (China); risk factors; screen printing; 2-methoxyethyl acetate
Descriptors (secondary) personal sampling; cleaning agents; determination in air; exposure evaluation; case-control study; solvents
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Paper-making and printing
Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Esters and salts
Printing, photography and photocopying industry