| Document ID (ISN) | 109542 |
| CIS number |
09-626 |
| ISSN - Serial title |
1556-3650 - Clinical Toxicology |
| Year |
2009 |
| Convention or series no. |
|
| Author(s) |
Pizon A.F., Schwartz A.R., Shum L.M., Rittenberger J.C., Lower D.R., Giannoutsos S., Virji M.A., Krasowski M.D. |
| Title |
Toxicology laboratory analysis and human exposure to p-chloroaniline |
| Bibliographic information |
Feb. 2009, Vol.47, No.2, p.132-136. Illus. 12 ref. |
| Abstract |
A 20 year-old man working at a chemical waste plant developed dizziness, abdominal pain and nausea. Following medical examinations which revealed cyanosis and methaemoglobinaemia, methylene blue administration led to complete recovery without sequelae. p-Chloroaniline was later identified as the chemical involved. The subject denied direct contact with the chemical, but was not wearing a respirator during work. GC/MS (gas chromatography-mass spectrometry) confirmed p-chloroaniline and its primary metabolite, p-chloroacetanilide, in the patient's urine. |
| Descriptors (primary) |
p-chloroaniline; toxicology; methaemoglobinaemia; chemical products; waste disposal; hypoxia |
| Descriptors (secondary) |
airborne dust; mass spectrometry; case study; metabolic process; determination in urine; diagnosis; respirators; sampling and analysis; gas chromatography; methylene blue |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Waste collection and disposal
Toxicology
Diseases of the respiratory system (except for pneumoconiosis & similar)
Blood diseases
|
