|Document ID (ISN)||109497|
|ISSN - Serial title
||1059-924X - Journal of Agromedicine
|Convention or series no.
||McCauley L.A., Lasarev M., Muniz J., Nazar Stewart V., Kisby G.
||Analysis of pesticide exposure and DNA damage in immigrant farmworkers
||2008, Vol.13, No.4, p.237-246. Illus. 33 ref.
||This study was designed to use the comet assay to describe the association of markers of DNA damage in oral leukocytes with biomarkers of pesticide exposure. It involved 134 farmworkers working in berry crops in the U.S. State of Oregon and 55 non exposed controls. It also examined the extent of DNA damage in young workers compared to adults and the effect of work histories, lifestyle factors, and diet on markers of DNA damage. Tail intensity and tail moment were significantly higher for agricultural workers compared to controls. However no parameter was significantly associated with years spent working in agriculture, age, sex, body mass index, diet, and alcohol or tobacco use. The results of this study demonstrate the feasibility for using the comet assay in biomonitoring studies of farmworkers.
||leukocytes; Oregon; organophosphorus compounds; agriculture; pesticides; insecticides; DNA
||captan; USA; reliability; determination in urine; case-control study; description of technique; questionnaire survey
||D - Periodical articles
|Country / State or Province||USA|
||Agriculture, fishing, animal husbandry
Toxic and dangerous substances
|Broad subject area(s)