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Document ID (ISN)109356
CIS number 09-395
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2007
Convention or series no.
Author(s) Multigner L., Ben Brik E., Arnaud I., Haguenoer J.M., Jouannet P., Auger J., Eustache F.
Title Glycol ethers and semen quality: A cross-sectional study among male workers in the Paris municipality
Bibliographic information July 2007, Vol.64, No.7, p.467-473. 39 ref.
Abstract This study investigated the effects of past and current exposure to products containing glycol ethers on semen quality and reproductive hormones among men employed by the Paris Municipality. Between 2000 and 2001, 109 male volunteers provided semen, blood and urine samples and underwent a medical examination. Information on lifestyle, occupation, exposure and medical history was obtained by interview. According to their job and chemical products used during the period 1990-2000, participants were classified as either historically exposed or non-exposed. Current exposure levels to glycol ethers were evaluated by monitoring urinary metabolites. Previous exposure to glycol ethers was associated with declines in sperm concentration, motility and morphologically-normal sperm levels. No effect of previous glycol ether exposure on hormones levels was observed. By contrast, current glycol ether exposure levels were low and not correlated with either seminal quality or hormone levels.
Descriptors (primary) antifertility effects; male workers; risk factors; glycol ethers; androgens; France
Descriptors (secondary) anamnesis; spermatogenic disturbances; exposure evaluation; cross-sectional study; determination in urine; determination in blood; medical examinations; exposure tests; urinary metabolites
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Glycol ethers
Genetic factors in reaction to exposures