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Document ID (ISN)109344
CIS number 09-424
ISBN(s) 978-92-4-153074-3
Year 2008
Convention or series no. Concise International Chemical Assessment Document 74
Author(s) Kielhorn J., Mangelsdorf I., Ziegler-Skylakakis K.
Title 2-Butenal
Bibliographic information World Health Organization, Distribution and Sales Service,1211 Genève 27, Switzerland, 2008. v, 47p. Illus. Approx. 200 ref.
Internet access http://www.who.int/ipcs/publications/cicad/cicad74.pdf [in English]
Abstract Conclusions of this criteria document: 2-Butenal causes irritation and inflammation of the skin, respiratory tract and eyes in humans and experimental animals. Its strong odour and irritancy may limit exposure to this substance. Most studies identified a genotoxic potential of 2-butenal. Positive results were found in a range of in vitro tests for genotoxicity. Owing to a lack of reliable data, it is not possible to adequately evaluate the toxicity of 2-butenal in humans or to derive a tolerable concentration. Summaries in French and in Spanish.
Descriptors (primary) WHO; crotonaldehyde; ecotoxicology; toxicology; aliphatic aldehydes
Descriptors (secondary) mutagenic effects; irritants; ILO; UNEP; genetic effects; fungicides; animal experiments; in vitro experiments; inhalation
Document type E - Books, reports, proceedings
Country / State or ProvinceWHO
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Genetic factors in reaction to exposures
Aldehydes
Pollution control