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CISDOC database

Document ID (ISN)109323
CIS number 09-390
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2008
Convention or series no.
Author(s) Rabinowitz P.M., Galusha D., Slade M.D., Dixon-Ernst C., O'Neill A., Fiellin M., Cullen M.R.
Title Organic solvent exposure and hearing loss in a cohort of aluminium workers
Bibliographic information Apr. 2008, Vol.65, No.4, p.230-235. 18 ref.
Abstract This retrospective cohort study was undertaken to examine the relationship between solvent exposure and hearing loss among workers of a large aluminium producer in the United States. A cohort of 1319 workers aged 35 years or less at inception was followed for five years. Typical solvent exposures involved mixtures of xylene, toluene and methyl ethyl ketone. Subjects were classified as solvent exposed or not on the basis of industrial hygiene records linked with individual job histories. Hearing levels were assessed using pure tone audiometry. Data were subjected to univariate and multivariate logistic models. Findings show that exposure to organic solvents is a risk factor for high frequency hearing loss, although the data do not allow conclusions about dose-response relationships.
Descriptors (primary) aluminium industry; risk factors; hearing loss; organic solvents
Descriptors (secondary) USA; butanone; toluene; xylene; statistical evaluation; cohort study; long-term study; pure-tone audiometry; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Metal production and metalworking
Noise, hearing and vibration
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Physical hazards
Browse category(ies) Smelting and refining operations
Diseases of the ear and hearing damage