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Document ID (ISN)109301
CIS number 09-294
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2007
Convention or series no.
Author(s) Schulte P.A., Kelsey K.T., Vainio H.
Title The contributions of genetics and genomics to occupational safety and health - Genetics and occupational safety and health - Genetics and occupational health and safety
Bibliographic information Nov. 2007, Vol.64, No.11, p.717-718; p.720-722. 32 ref.
Abstract This editorial and the two comments it elicited discuss the contributions of genetics and genomics to occupational health. Genetic factors contribute to the variable responses of workers to occupational hazards - particularly chemical hazards, together with some biological and physical agents. Workers with susceptible genetic profiles may still be at unacceptably high risk even if exposed to low concentrations. There is a broad range of published evidence showing that genetic polymorphisms can lead to differential occupational disease risks in exposed workers. However collecting information on workers' genetic susceptibility raises ethical and legal questions about the way this information should be used.
Descriptors (primary) genetic effects; medical supervision; individual susceptibility
Descriptors (secondary) legal aspects; ethics; genetic screening
Document type D - Periodical articles
Country / State or ProvinceFinland; USA
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Biological hazards
Physical hazards
Chemical safety
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Ethical issues