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CISDOC database

Document ID (ISN)109190
CIS number 09-166
ISBN(s) 978-92-4-156349-9
Year 2007
Convention or series no.
Author(s)
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
Title IPCS mode of action framework
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2007. iv, 123p. Illus. Bibl.ref. Price: CHF 40.00 (CHF 28.00 in developing countries).
Internet access http://www.who.int/ipcs/ [in English]
Abstract The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This manual presents two IPCS frameworks. Part 1 contains the framework for analysing the relevance of a cancer mode of action for humans, along with three case studies illustrating its application. Part 2 contains the framework for analysing the relevance of a non-cancer mode of action for humans. These frameworks provide a means of ensuring a transparent evaluation of the data, the identification of key data gaps and information that would be of value in the further risk assessment of the chemical in question.
Descriptors (primary) dangerous substances; carcinogens; health hazards; chemical products; hazard evaluation; IPCS
Descriptors (secondary) ILO; description of technique; WHO
Document type E - Books, reports, proceedings
Country / State or ProvinceWHO
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Risk evaluation