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Document ID (ISN)109123
CIS number 09-35
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2008
Convention or series no.
Author(s) Weinmann S., Vollmer W.M., Breen V., Heumann M., Hnizdo E., Villnave J., Doney B., Graziani M., McBurnie M.A., Buist A.S.
Title COPD and occupational exposures: A case-control study
Bibliographic information May 2008, Vol.50, No.5, p.561-569. Illus. 34 ref.
Abstract This case-control study evaluated the association between occupational exposures and chronic obstructive pulmonary disease (COPD) based on lifetime occupational history. A total of 388 cases aged 45 years and older with COPD were compared with 356 controls matched by age, sex and smoking history. Odds ratios for exposure to eight occupational hazard categories and three composite measures of exposure were computed using logistic regression. Occupational exposures most strongly associated with COPD were diesel exhaust, irritant gases and vapors, mineral dust and metal dust. The composite measures describing aggregate exposure to gases, vapors, solvents, or sensitizers (GVSS) and aggregate exposure to dust, GVSS, or diesel exhaust were also associated with COPD. In the small group of never-smokers, a similar pattern was evident.
Descriptors (primary) obstructive ventilatory impairment; risk factors; occupation disease relation
Descriptors (secondary) airborne dust; irritants; diesel engines; smoking; statistical evaluation; exhaust gases; case-control study; confounding factors; solvents
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)