|Document ID (ISN)||109115|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Hamaguchi T., Omae K., Takebayashi T., Kikuchi Y., Yoshioka N., Nishiwaki Y., Tanaka A., Hirata M., Taguchi O., Chonan T.
||Exposure to hardly soluble indium compounds in ITO production and recycling plants is a new risk for interstitial lung damage
||Jan. 2008, Vol.65, No.1, p.51-55. Illus. 24 ref.
||The objective of this case-control study was to identify the effects of indium on the lung and to assess possible dose-response relationships. It involved 93 male indium-exposed and 93 male non-exposed workers from four indium and tin oxide manufacturing and recycling plants. Indium in serum (In-S) was determined as a biomarker of exposure. Geometric means of In-S were 8.25ng/ml in the exposed workers and 0.25ng/ml in the non-exposed workers. The maximum concentration of In-S was 116.9ng/ml. Data on respiratory symptoms and job histories were obtained by means of questionnaires. Participants were also subjected to spirometry, high-resolution computerised tomography (HRCT) of the chest, serum KL-6, serum SP-A, serum SP-D and serum CRP. Serum biomarkers and HRCT indicate that exposure to hardly-soluble indium compound dust may represent a risk for interstitial lung damage. Other findings are discussed.
||indium and compounds; tin oxide; risk factors; pulmonary fibrosis; metalworking industry; Japan
||airborne dust; subjective assessment; symptoms; respiratory diseases; respirable dust; tomography; case-control study; spirometry; determination in blood; medical examinations; exposure tests; questionnaire survey
||D - Periodical articles
|Country / State or Province||Japan|
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)