|Document ID (ISN)||109060|
|Convention or series no.
||Harmonization Project Document No.5
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
||Skin sensitization in chemical risk assessment
||World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2008. iv, 85p. Illus. Bibl.ref.
||http://www.who.int/ipcs/methods/harmonization/areas/skin_sensitization.pdf [in English]
||This harmonization project activity in 2006 focused on skin sensitization in chemical risk assessment. An IPCS international workshop was convened from 17-18 October 2006, in Berlin, Germany with the aim of evaluating experimental techniques for their ability to produce data to inform risk assessment, including provision of dose-response information and information relating to sensitive sub-populations. The workshop focused on whether it is possible to distinguish between chemicals with a high potency to elicit allergic skin reactions and those with a low potency. Emerging approaches, such as structure activity relationships (SAR), were explored. The meeting also explored whether assessment approaches for skin sensitization could inform approaches for the respiratory tract.
||WHO; skin allergies; skin tests; chemical products; hazard evaluation; sensitizers
||allergens; IPCS; sensitization; dose-response relationship; conference; reliability
||E - Books, reports, proceedings
|Country / State or Province||WHO|
||Toxic and dangerous substances
|Broad subject area(s)