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Document ID (ISN)109013
CIS number 09-115
ISSN - Serial title 1545-9624 - Journal of Occupational and Environmental Hygiene
Year 2007
Convention or series no.
Author(s) Sutton P.M., Quint J., Prudhomme J., Flattery J., Materna B., Harrison R.
Title Glutaraldehyde exposures among workers making bioprosthetic heart valves
Bibliographic information May 2007, Vol.4, No.5, p.311-320. Illus. 41 ref.
Abstract This investigation was undertaken to describe exposure to glutaraldehyde among workers making bioprosthetic heart valves at two large manufacturers in California. The work process was observed, employer representatives and glutaraldehyde-exposed workers were interviewed, and employer records including industrial hygiene data were analyzed. Approximately 600 workers (mostly women) had continuous airborne exposure to glutaraldehyde. Short-term exposures were all well below the current regulatory ceiling level (0.20ppm). However, approximately 40% of the glutaraldehyde-related job tasks involved exposures above the ACGIH threshold limit value ceiling of 0.05ppm. Two cases of physician-diagnosed asthma were recorded in one company in the previous 5-year period. Employers should implement additional engineering controls to limit workers' exposures to at a maximum level of 0.015ppm, require the use of gloves and implement a medical surveillance programme for glutaraldehyde-exposed workers.
Descriptors (primary) glutaraldehyde; California; biotechnology industry; women; limitation of exposure
Descriptors (secondary) occupational hygiene; protective gloves; threshold limit values; USA; medical supervision; diagnosis; permissible levels; ventilation systems; exposure evaluation; asthma
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aldehydes
Biotechnology industry