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Document ID (ISN)108895
CIS number 08-1382
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2008
Convention or series no.
Author(s) Lohi J., Kyyr÷nen P., Kauppinen T., Kujala V., Pukkala E.
Title Occupational exposure to solvents and gasoline and risk of cancers in the urinary tract among Finnish workers
Bibliographic information Sep. 2008, Vol.51, No.9, p.668-672. 15 ref.
Abstract The aim of this study was to estimate the risk of cancers of the urinary tract in relation to occupational exposure to solvents and gasoline. A cross-sectional cohort of all economically active Finns from the 1970 population census was followed up for bladder cancer (BC, 10,277 cases) and renal cell cancer (RCC, 9954 cases). Exposure to hydrocarbons solvents and gasoline were assessed with a job exposure matrix. Relative risks (RR) were defined using Poisson regression models, adjusted for smoking and obesity. Exposure to solvents was positively associated with the incidence of BC in women but not in men. The RRs were above 1.2 in nearly all exposures studied but a statistically significant excess was only seen for middle levels of chlorinated solvents (1.7) and low levels of aromatic solvents (1.6). The RRs for RCC were close to unity in all exposures studied.
Descriptors (primary) Finland; renal cancer; risk factors; motor fuel; solvents; bladder tumour
Descriptors (secondary) aromatic hydrocarbons; cohort study; statistical evaluation; sex-linked differences; job-exposure relation; chlorinated hydrocarbons
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the kidney and the urinary system