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Document ID (ISN)108894
CIS number 08-1291
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2008
Convention or series no.
Author(s) Kubale T., Hiratzka S., Henn S., Markey A., Daniels R., Utterback D., Waters K., Silver S., Robinson C., Macievic G., Lodwick J.
Title A cohort mortality study of chemical laboratory workers at Department of Energy nuclear plants
Bibliographic information Sep. 2008, Vol.51, No.9, p.656-667. 39 ref.
Abstract This study evaluated the mortality causes of 6157 chemical laboratory workers employed at United States Department of Energy facilities. All cause, all cancer and cause-specific standardized mortality ratios were calculated. Cox regression analyses were conducted to further evaluate the relation between chemical exposure and mortality risk due to selected cancers. The mortality due to all causes combined and all cancers combined were below expectation for the cohort. There were no statistically significant elevations reported among men for any specific cancer or non-cancer outcome. Neither were there any statistically significant elevations among women for any specific non-cancer and most specific cancers; however, multiple myeloma deaths were significantly elevated (SMR=3.56). Statistically significant elevations of leukaemia were observed among workers employed 20 years or more, together with a statistically-significant trend of elevated lung cancer mortality with increasing employment duration. Other findings are discussed.
Descriptors (primary) USA; laboratory work; nuclear power stations; chemical products; mortality
Descriptors (secondary) leukaemia; myeloma; length of service; frequency rates; cohort study; sex-linked differences; statistical evaluation; cancer
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Power generation and distribution