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Document ID (ISN)108775
CIS number 08-1301
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2008
Convention or series no.
Author(s) Fireman E., Lerman Y., Stark M., Schwartz Y., Ganor E., Grinberg N., Frimer R., Landau D.A., Zilberberg M., Barenboim E., Jacovovitz R.
Title Detection of occult lung impairment in welders by induced sputum particles and breath oxidation
Bibliographic information July 2008, Vol.51, No.7, p.503-511. Illus. 43 ref.
Abstract This study evaluated particulate matter in combined induced sputum (IS) and oxidation in exhaled breath condensate (EBC), in order to test whether underlying inflammatory changes are present in asymptomatic welders. Thirty welders from the Israel Defence Forces exposed to aluminium/iron (Group 1), 16 exposed to cadmium/chromium/iron/lead/nickel (Group 2) and 27 non-exposed administrative staff were studied. IS was recovered and particle size distribution, hydrogen peroxide and pH were measured; exhaled breath condensate also was collected. Group 2 had a higher percentage of neutrophils than all other participants and a higher percentage of particles of more than 2µm in diameter. Percent particles and years of exposure highly correlated. All welders' EBC samples had higher concentrations of hydrogen peroxide than controls. Other findings are discussed.
Descriptors (primary) Israel; metal fumes; welding and cutting; exposure tests; respiratory impairment; defence services
Descriptors (secondary) particle size distribution; hydrogen peroxide; expectoration; determination in exhaled air; case-control study; blood cytology; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceIsrael
Subject(s) Metal production and metalworking
Broad subject area(s) Occupational medicine, epidemiology
Industries and occupations
Chemical safety
Browse category(ies) Welding and cutting
Biological monitoring
Diseases of the respiratory system (except for pneumoconiosis & similar)
Fire fighting, police, prisons and the armed forces