| Document ID (ISN) | 108749 |
| CIS number |
08-1170 |
| ISSN - Serial title |
1232-1966 - AAEM - Annals of Agricultural and Environmental Medicine |
| Year |
2007 |
| Convention or series no. |
|
| Author(s) |
Kłuciński P., Mazur B., Hrycek A., Maśluch E., Cieślik P., Kaufman J., Martirosian G. |
| Title |
Expression of cellular isoform of prion protein on the surface of peripheral blood lymphocytes among women exposed to low doses of ionizing radiation |
| Bibliographic information |
Dec. 2007, Vol.14, No.2, p.225-228. 27 ref. |
| Abstract |
The objective of this case-control study was to determine the effect of low doses of ionizing radiation on the expression of cellular isoform prion protein (PrPc) found on surface peripheral blood lymphocytes of women operating X-ray equipment. It involved 36 exposed women and 30 unexposed controls, also women. The PrPc expression on CD3 (T lymphocytes), CD4 (T helper), CD8 (T cytotoxic) and CD19 (B lymphocytes) as well as the percentage of lymphocytes with PrPc on their surface were tested. A significant increase in PrPc expression on CD3 and CD4 with lowered PrPc level on CD8 and in percentage of CD8 cells with PrPc were observed among exposed subjects compared to controls. Other findings are discussed. |
| Descriptors (primary) |
ionizing radiation; proteins; women; x-ray equipment; lymphocytes |
| Descriptors (secondary) |
length of service; case-control study; determination in blood; sampling and analysis; job-exposure relation |
| Document type |
D - Periodical articles |
| Country / State or Province | Poland |
| Subject(s) |
Radiation
|
| Broad subject area(s) |
Physical hazards
|
| Browse category(ies) |
Ionizing radiation
|
