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Document ID (ISN)108443
CIS number 08-933
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2007
Convention or series no.
Author(s) Telle-Lamberton M., Samson E., CaŰr S., Bergot D., Bard D., Bermann F., GÚlas J.M., Giraud J.M., Hubert P., Metz-Flamant C., NÚron M.O., Quesne B., Tirmache M., Hill C.
Title External radiation exposure and mortality in a cohort of French nuclear workers
Bibliographic information Oct. 2007, Vol.64, No.10, p.694-700. Illus. 31 ref.
Abstract The objective of this study was to analyse the effect of external radiation exposure on the mortality of French nuclear workers. A cohort of 29,204 workers employed between 1950 and 1994 at the French Atomic Energy Commission (CEA) or at the General Company of Nuclear Fuel (Areva) was followed up for an average of 17.8 years. Standardized mortality ratios were computed with reference to French mortality rates. Dose-effect relationships were analysed through trend tests and Poisson regression, with linear and log-linear models. A healthy worker effect was observed, the number of deaths in the cohort being 59% of the number expected from national mortality statistics. Among the 21 main cancer sites studied, a statistically significant excess was observed only for skin melanoma, while an excess of borderline statistical significance was observed for multiple myeloma. A dose-effect relationship was observed for leukaemia after exclusion of chronic lymphoid leukaemia. Other findings are discussed.
Descriptors (primary) France; mortality; risk factors; cancer; nuclear power stations; nuclear fuel processing
Descriptors (secondary) ionizing radiation; melanoma; healthy worker effect; leukaemia; statistical evaluation; exposure evaluation; cohort study; long-term study; dose-response relationship; myeloma
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Radiation
Broad subject area(s) Physical hazards
Industries and occupations
Occupational medicine, epidemiology
Browse category(ies) Power generation and distribution