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CISDOC database
Document ID (ISN) | 108351 |
CIS number |
08-826 |
ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
Year |
2007 |
Convention or series no. |
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Author(s) |
Orsi L., Troussard X., Monnereau A., Berthou C., Fenaux P., Marit G., Soubeyran P., Huguet F., Milpied N., Leporrier M., Hemon D., Clavel J. |
Title |
Occupation and lymphoid malignancies: Results from a French case-control study |
Bibliographic information |
Dec. 2007, Vol.49, No.12, p.1339-1350. 41 ref. |
Abstract |
To investigate potential relationships between occupational risk factors and lymphoid malignancy (LM), a multicentre hospital-based case-control study was conducted in France between 2000 and 2004, including 824 incident cases of non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), multiple myeloma and lymphoproliferative syndrome, and 752 matched controls. Data were collected through face-to-face interviews and subjected to statistical evaluation. It was found that farming was significantly associated with NHL (odds ratio OR 1.4) and, although not significantly, with lymphoproliferative syndrome and multiple myeloma. ORs were higher for longest durations of exposure. Self-declared exposure to pesticides was significantly associated with NHL (OR 1.8) and HL (OR 2.2). Neither solvent-related jobs nor self-reported exposure to solvents were related to LM. Systematic screening based on job titles did not evidence any other association. The results support the hypothesis that farming plays a role in most types of LM. |
Descriptors (primary) |
leukaemia; cancer; occupation disease relation; France |
Descriptors (secondary) |
subjective assessment; lymphoma; Hodgkin's disease; myeloma; pesticides; statistical evaluation; case-control study; hospitals; risk factors; agriculture; length of exposure; solvents |
Document type |
D - Periodical articles |
Country / State or Province | France |
Subject(s) |
Occupational pathology
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Broad subject area(s) |
Occupational medicine, epidemiology
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Browse category(ies) |
Leukaemia
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