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Document ID (ISN)108351
CIS number 08-826
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2007
Convention or series no.
Author(s) Orsi L., Troussard X., Monnereau A., Berthou C., Fenaux P., Marit G., Soubeyran P., Huguet F., Milpied N., Leporrier M., Hemon D., Clavel J.
Title Occupation and lymphoid malignancies: Results from a French case-control study
Bibliographic information Dec. 2007, Vol.49, No.12, p.1339-1350. 41 ref.
Abstract To investigate potential relationships between occupational risk factors and lymphoid malignancy (LM), a multicentre hospital-based case-control study was conducted in France between 2000 and 2004, including 824 incident cases of non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), multiple myeloma and lymphoproliferative syndrome, and 752 matched controls. Data were collected through face-to-face interviews and subjected to statistical evaluation. It was found that farming was significantly associated with NHL (odds ratio OR 1.4) and, although not significantly, with lymphoproliferative syndrome and multiple myeloma. ORs were higher for longest durations of exposure. Self-declared exposure to pesticides was significantly associated with NHL (OR 1.8) and HL (OR 2.2). Neither solvent-related jobs nor self-reported exposure to solvents were related to LM. Systematic screening based on job titles did not evidence any other association. The results support the hypothesis that farming plays a role in most types of LM.
Descriptors (primary) leukaemia; cancer; occupation disease relation; France
Descriptors (secondary) subjective assessment; lymphoma; Hodgkin's disease; myeloma; pesticides; statistical evaluation; case-control study; hospitals; risk factors; agriculture; length of exposure; solvents
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Leukaemia