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Document ID (ISN)108349
CIS number 08-768
Year 2007
Convention or series no.
Agency for Toxic Substances and Disease Registry (ATSDR)
Title Toxicological profile for lead (Update)
Bibliographic information U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Division of Toxicology/Toxicology Information Branch, 1600 Clifton Road NE, E-29, Atlanta, GA 30333, USA, Aug. 2007. xx, 528p. Illus. Approx. 1700 ref. Index.
Internet access [in English]
Abstract This profile has been prepared in accordance with guidelines set by the US Agency for Toxic Substances and Disease Registry and the EPA. The key literature related to the toxic effects of lead is identified and reviewed. Contents: public health statement; health effects; chemical and physical information; production, import, use and disposal; potential for human exposure; analytical methods; regulations and advisories; glossary. Health hazards include: brain damage (neurotoxic effects, encephalopathy); renal damage; haematotoxic effects (anaemia); damage to the male reproductive system; retarded development of newborn children. IARC classifies organic lead compounds as possible human carcinogens (group 2B), while inorganic lead compounds are not classifiable with respect to their human carcinogenicity because of insufficient evidence. (Update of CIS 96-2227).
Descriptors (primary) USA; lead and compounds; health hazards; toxicology; toxicity evaluation; lead
Descriptors (secondary) toxic effects; criteria document; literature survey; antifertility effects; children; IARC; anaemia; encephalopathy; brain tissue damage; renal damage; limitation of exposure; exposure evaluation; teratogenic effects; haematotoxic effects; glossary; neurotoxic effects
Document type B - Chemical safety information sheets
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Genetic factors in reaction to exposures
Lead and compounds
Inorganic substances