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Document ID (ISN)108344
CIS number 08-763
Year 2007
Convention or series no.
Author(s)
Agency for Toxic Substances and Disease Registry (ATSDR)
Title Toxicological profile for acrolein (Update)
Bibliographic information U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Division of Toxicology/Toxicology Information Branch, 1600 Clifton Road NE, E-29, Atlanta, GA 30333, USA, Aug. 2007. xx, 176p. Illus. Approx. 420 ref. Index.
Internet access http://www.atsdr.cdc.gov/toxprofiles/tp124.pdf [in English]
Abstract This profile has been prepared in accordance with guidelines set by the US Agency for Toxic Substances and Disease Registry and the EPA. The key literature related to the toxic effects of acrolein is identified and reviewed. Contents: public health statement; health effects; chemical and physical information; production, import, use and disposal; potential for human exposure; analytical methods; regulations and advisories; glossary. Health hazards include: eye and skin irritation, ulceration and necrosis; irritation of the gastrointestinal tract; irritation of the respiratory tract; pulmonary oedema and lung haemorrhage, possibly leading to death; in vitro studies shows the product to be weakly mutagenic; IARC has stated that the product is not classifiable as to carcinogenicity in humans. (Update of CIS 91-1256).
Descriptors (primary) USA; toxicology; acrolein; health hazards; toxicity evaluation
Descriptors (secondary) mutagenic effects; toxic effects; literature survey; IARC; irritation; criteria document; limitation of exposure; exposure evaluation; respiratory impairment; glossary; necrosis
Document type B - Chemical safety information sheets
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aldehydes
Genetic factors in reaction to exposures