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Document ID (ISN)108185
CIS number 08-573
ISSN - Serial title 0339-6517 - Documents pour le médecin du travail
Year 2007
Convention or series no. DMT 112 TR 40
Author(s) Rosenberg N.
Title Occupational asthma due to enzymes
Original title Asthme professionnel aux enzymes [in French]
Bibliographic information 4th Quarter 2007, No.112, p.553-564. 64 ref.
Internet access http://www.dmt-prevention.fr/inrs-pub/inrs01.nsf/IntranetObject-accesParReference/TR%2040/$File/TR40.pdf [in French]
Abstract Enzymes are used in many industries and activities. Whenever they are handled as powders or aerosols, there is a risk of respiratory sensitization. Sensitization is due to their protein structure and not to their enzymatic activity. The sectors of activity most frequently involved are the detergents industry, enzyme production, biotech research, the pharmaceutical industry and the food industry, particularly the bakery products industry. Diagnosis is based on symptoms, exposure to enzymes in powered or aerosol form and positive skin or blood tests. Atopy constitutes a risk factor but enzyme asthma is always the result of deficient working conditions; its prevention requires strict workplace hygiene. Rhinitis and asthma caused by enzymes are recognized as occupational diseases in France.
Descriptors (primary) proteins; occupational diseases; risk factors; occupation disease relation; asthma; enzymes
Descriptors (secondary) occupational hygiene; sensitization; airborne dust; compensation of occupational diseases; rhinitis; laboratory work; France; enzyme activity; aerosols; diagnosis; conditions of work; skin tests; research; individual susceptibility; food industry; determination in blood; biotechnology industry; detergent industry; bakery products industry
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Broad subject area(s) Biological hazards
Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Biotechnology industry