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CISDOC database

Document ID (ISN)107894
CIS number 08-386
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2006
Convention or series no.
Author(s) Veraldi A., Seniori Costantini A., Bolejack V., Miligi L., Vineis P., van Loveren H.
Title Immunotoxic effects of chemicals: A matrix for occupational and environmental epidemiological studies
Bibliographic information Dec. 2006, Vol.49, No.12, p.1046-1055. 38 ref.
Abstract This literature survey based on 227 animal studies and 94 human studies evaluates the immunotoxicity of benzene, trichloroethylene, PAHs, crystalline silica, diesel exhausts, welding fumes, asbestos, styrene, formaldehyde, toluene, vinyl chloride monomer tetrachloroethylene, chlorophenols, 1,3-butadiene, mineral oils, p-dichlorobenzene, dichloromethane, xylene, 1,1,1-trichloroethane and ethylene oxide. These substances were then classified on the basis of the evidence of toxicity and type of immunotoxic effects (immunosuppression, autoimmunity, hypersensitivity) on the basis of the immune responses. Finally substances were assigned an index of immunotoxic potency.
Descriptors (primary) toxicology; immunotoxic effects; chemical products
Descriptors (secondary) literature survey; classification; diesel engines; dichloromethane; 1,1,1-trichloroethane; vinyl chloride; trichloroethylene; tetrachloroethylene; dichlorobenzene; aromatic hydrocarbons; benzene; toluene; styrene; butadiene; silica; mineral oils; asbestos; autoimmunization; ethylene oxide; exhaust gases; welding fumes; xylene; polycyclic hydrocarbons; chlorophenols; hypersensitivity; formaldehyde
Document type D - Periodical articles
Country / State or ProvinceUnited Kingdom; Italy; Netherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Butadiene