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CISDOC database
| Document ID (ISN) | 107693 |
| CIS number |
08-84 |
| ISSN - Serial title |
0105-1873 - Contact Dermatitis |
| Year |
2006 |
| Convention or series no. |
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| Author(s) |
Geier J., Lessmann H., Becker D., Bruze M., Frosch P.J., Fuchs T., Jappe U., Koch P., Pföhler C., Skudlik C. |
| Title |
Patch testing with components of water-based metalworking fluids: Results of a multicentre study with a second series |
| Bibliographic information |
Dec. 2006, Vol.55, No.6, p.322-329. 33 ref. |
| Abstract |
This study investigated sensitization to ten frequently-used metalworking fluid (MWF) components, which are not part of the established MWF test series, in metalworkers with suspected occupational dermatitis due to MWF. Seven patients reacted positively to 4,4'-methylene bis morpholine, including six who also reacted to formaldehyde and/or other formaldehyde releasers. Four patients reacted positively to myristyl alcohol. Additionally, 20 doubtful or irritant reactions occurred. One patient each reacted positively to oleyl alcohol, monoisopropanolamine and 2-amino-2-ethyl- 1,3-propanediol. None of the other substances tested elicited any clear-cut positive reaction. Patch testing with well-known MWF allergens showed proportions of positive reactions, which were comparable to those from other studies, e.g. 11 % to monoethanolamine, 8% to colophony and 3-5% to various preservatives. |
| Descriptors (primary) |
additives; cutting fluids; sensitization; preservatives; metalworking industry |
| Descriptors (secondary) |
formaldehyde; frequency rates; myristyl alcohol; oleyl alcohol; N,N'-methylenebismorpholine; Germany; 2-amino-2-ethyl-1,3 propanediol; ethanolamine; isopropanolamine; colophony; carbamol; sensitizers; allergy tests; skin tests; irritants |
| Document type |
D - Periodical articles |
| Country / State or Province | Germany |
| Subject(s) |
Metal production and metalworking
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| Broad subject area(s) |
Chemical safety
Occupational medicine, epidemiology
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| Browse category(ies) |
Metalworking industry
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