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CISDOC database

Document ID (ISN)107654
CIS number 08-76
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) Pietroiusti A., Forlini A., Magrini A., Galante A., Coppeta L., Gemma G., Romeo E., Bergamaschi A.
Title Shift work increases the frequency of duodenal ulcer in H. pylori infected workers
Bibliographic information Nov. 2006, Vol.63, No.11, p.773-775. 12 ref.
Abstract The objective of this study was to evaluate whether shift work is associated with an increased rate of peptic ulcer in H. pylori infected workers. During a two year period, workers with persistent dyspeptic symptoms underwent non-invasive evaluation of H. pylori status. The workers testing positive were included in the study and divided into 247 day workers and 101 shift workers. In all workers, a gastrointestinal endoscopy was performed and biopsy specimens were taken from the stomach. It was found that the prevalence of duodenal ulcer was significantly higher in shift workers than in day-time workers (odds ratio OR=3.92) and persisted after multivariate analysis, taking into account possible confounding factors (OR=3.96). It is concluded that shift work increases the ulcerogenic potential of H. pylori infection and should be considered a risk factor for duodenal ulcer in infected shift workers.
Descriptors (primary) bacterial diseases; risk factors; peptic ulcer; shift work
Descriptors (secondary) symptoms; case-control study; endoscopy; frequency rates; biopsy
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Biological hazards
Physiology, ergonomics
Browse category(ies) Bacterial and parasitic diseases
Gastrointestinal diseases