ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)107600
CIS number 08-144
ISSN - Serial title 0465-546X - Medicina y seguridad del trabajo
Year 2007
Convention or series no.
Author(s) Blein Sánchez de León A., Arruga Laviña M.V.
Title Initial hygiene evaluation of acrylamide in air during the preparation of polyacrylamide (PAA) gel in a genetics laboratory
Original title Evaluación higiénica previa de acrilamida en aire durante la preparación de gel de poliacrilamida (PAA) en un laboratorio de genética [in Spanish]
Bibliographic information June 2007, Vol.LIII, No.207, p.47-52. 16 ref.
Abstract The objective of this study was to evaluate the level of acrylamide, classified by IARC as a type 2A carcinogen (probably carcinogenic to humans) in workplace air during the preparation of polyacrylamide gel in a genetics laboratory in Spain. Sampling and analyses were carried out using the NIOSH procedure PV2004 involving sorbent tubes, desorption and analysis by high performance liquid chromatography using an ultraviolet detector. The detected level of acrylamide in the weighing stage was found to be 723% of the TLV TWA and 145% of the TLV-C. No acrylamide was detected in the stirring stage. Based on these findings, several preventive measures were proposed for immediate implementation.
Descriptors (primary) laboratory work; acrylamide; determination in air; exposure evaluation
Descriptors (secondary) threshold limit values; carcinogens; high performance chromatography; sampling and analysis; IARC; limitation of exposure; public OSH institutions
Document type D - Periodical articles
Country / State or ProvinceSpain
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Amides
Exposure evaluation