|Document ID (ISN)||107585|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Tse L.A., Yu I.T.S., Leung C.C., Tam W., Wong T.W.
||Mortality from non-malignant respiratory diseases among people with silicosis in Hong Kong: Exposure-response analyses for exposure to silica dust
||Feb. 2007, Vol.64, No.2, p.87-92. 35 ref.
||The objective of this study was to examine the exposure-response relationships between exposure to silica dust and the mortality from non-malignant respiratory diseases (NMRDs) and chronic obstructive pulmonary diseases (COPDs) among a cohort of 2789 workers with silicosis in Hong Kong. Exposures in each industry were evaluated on the basis of historical industrial hygiene data. Exposure indices included cumulative dust exposure (CDE) and mean dust concentration (MDC). Findings were subjected to statistical analyses. From 1981 to 1999, there were 371 deaths from NMRDs in the cohort, of which and 101 were COPDs. CDE and MDC were significantly associated only with NMRD mortality. Subgroup analysis showed that deaths were significantly associated with both CDE and MDC among underground caisson workers and among those with high exposure to silica dust. A clear upward trend was also found for both NMRDs and COPDs mortality with increasing severity of radiological silicosis.
||obstructive ventilatory impairment; mortality; risk factors; silicosis; respiratory diseases
||Hong Kong; airborne dust; silica; work in pressurized atmosphere; underground work; opacities; cohort study; fatalities; dose-response relationship; statistical evaluation; exposure evaluation
||D - Periodical articles
|Country / State or Province||Hong Kong|
|Broad subject area(s)
Occupational medicine, epidemiology
Diseases of the respiratory system (except for pneumoconiosis & similar)