ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)107585
CIS number 08-72
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2007
Convention or series no.
Author(s) Tse L.A., Yu I.T.S., Leung C.C., Tam W., Wong T.W.
Title Mortality from non-malignant respiratory diseases among people with silicosis in Hong Kong: Exposure-response analyses for exposure to silica dust
Bibliographic information Feb. 2007, Vol.64, No.2, p.87-92. 35 ref.
Abstract The objective of this study was to examine the exposure-response relationships between exposure to silica dust and the mortality from non-malignant respiratory diseases (NMRDs) and chronic obstructive pulmonary diseases (COPDs) among a cohort of 2789 workers with silicosis in Hong Kong. Exposures in each industry were evaluated on the basis of historical industrial hygiene data. Exposure indices included cumulative dust exposure (CDE) and mean dust concentration (MDC). Findings were subjected to statistical analyses. From 1981 to 1999, there were 371 deaths from NMRDs in the cohort, of which and 101 were COPDs. CDE and MDC were significantly associated only with NMRD mortality. Subgroup analysis showed that deaths were significantly associated with both CDE and MDC among underground caisson workers and among those with high exposure to silica dust. A clear upward trend was also found for both NMRDs and COPDs mortality with increasing severity of radiological silicosis.
Descriptors (primary) obstructive ventilatory impairment; mortality; risk factors; silicosis; respiratory diseases
Descriptors (secondary) Hong Kong; airborne dust; silica; work in pressurized atmosphere; underground work; opacities; cohort study; fatalities; dose-response relationship; statistical evaluation; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceHong Kong
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Pneumoconioses
Diseases of the respiratory system (except for pneumoconiosis & similar)