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Document ID (ISN)107576
CIS number 08-103
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) Lacasaña M., Vázquez-Grameix H., Borja-Aburto C.H., Blanco-Muñoz J., Romieu I., Aguilar-Garduño C., García A.M.
Title Maternal and paternal occupational exposure to agricultural work and the risk of anencephaly
Bibliographic information Oct. 2006, Vol.63, No.10, p.649-656. 43 ref.
Abstract The objective of this case-control study was to evaluate the association between parental occupational exposure to agricultural work and the risk of anencephaly. Cases included 151 children born with anencephaly in maternities of three Mexican states, while controls were births without congenital malformations from the same maternities. General information and information on exposures to pesticides were obtained by means of questionnaires. The children of mothers who worked in agriculture in the acute risk period during pregnancy had a significantly greater risk of anencephaly (odds ratio, OR 4.57). The risk of fathers having a child with anencephaly was greater among those who applied pesticides, irrespective of whether it was during or not during the acute risk period (OR 2.50 and 2.03 respectively).
Descriptors (primary) embryotoxic effects; parental exposure; agriculture; teratogenic effects; risk factors; pesticides
Descriptors (secondary) Mexico; expectant mothers; case-control study; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceSpain; Mexico
Subject(s) Agriculture, fishing, animal husbandry
Occupational pathology
Broad subject area(s) Industries and occupations
Occupational medicine, epidemiology
Chemical safety
Browse category(ies) Antifertility and prenatal effects
Agricultural chemicals
Genetic factors in reaction to exposures