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Document ID (ISN)107529
CIS number 08-151
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2007
Convention or series no.
Author(s) Milković-Kraus S., Macan J., Kanceljak-Macan B.
Title Occupational allergic contact dermatitis from azithromycin in pharmaceutical workers: A case series
Bibliographic information Feb. 2007, Vol.56, No.2, p.99-102. 16 ref.
Abstract A series of seven cases of occupational allergic contact dermatitis (ACD) caused by azithromycin in Croatian pharmaceutical workers is described. Seven out of 21 workers exposed to powdered intermediate and final substances in azithromycin synthesis were referred with workplace-related skin and respiratory symptoms. They all underwent a diagnostic procedure involving medical history and medical examinations, patch testing with standard allergens and azithromycin, prick testing with inhalatory allergens and total . ACD caused by azithromycin was established in four examined workers showing a positive patch test to azithromycin. Two workers additionally showed a positive patch test to intermediate substances. Other findings are discussed.
Descriptors (primary) allergens; azithromycin; antibiotics; sensitization; skin diseases; pharmaceutical industry; macrolide antibiotics
Descriptors (secondary) airborne dust; immunoglobulins; case study; individual susceptibility; eczema; skin tests; Croatia
Document type D - Periodical articles
Country / State or ProvinceCroatia
Subject(s) Chemicals, plastics and rubber
Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Pharmaceutical industry
Skin diseases