| Document ID (ISN) | 107463 |
| CIS number |
07-1252 |
| ISBN(s) |
978-3-7776-1530-1 |
| Year |
2007 |
| Convention or series no. |
BUA Report 262
|
| Author(s) |
Advisory Committee on Existing Chemicals (BUA) |
| Title |
Isopropylisocyanate |
| Bibliographic information |
S. Hirzel Verlag, Birkenwaldstrasse 44, 70191 Stuttgart, Germany, 2007. xiv, 40p. 79 ref. Price: EUR 00.00. Downloadable version free of charge. |
| Internet access |
http://www.dav-buchhandlung.de/... [in English]
|
| Abstract |
Conclusions of this criteria document which reflects the state of knowledge of November 2005: isopropyl isocyanate is highly irritating to the skin, eyes and respiratory tract. In male rats, the 5h LC50 is 499mg/m3 and the oral LD5l0 is 218mg/kg body weight in rats. Animal studies at high concentrations show adverse effects on the respiratory function. In mutagenicity tests, the product is non-mutagenic up to the toxic range. No data are available for an evaluation of the sensitization potential, genotoxicity, carcinogenicity and reproductive toxicity. |
| Descriptors (primary) |
toxic effects; ecotoxicology; isopropyl isocyanate; Germany |
| Descriptors (secondary) |
literature survey; criteria document; animal experiments; irritants |
| Document type |
B - Chemical safety information sheets |
| Country / State or Province | Germany |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Pollution control
Isocyanates
Cyano compounds
|
