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Document ID (ISN)107391
CIS number 07-1377
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2007
Convention or series no.
Author(s) Gresie-Brusin D.F., Kielkowski D., Baker A., Channa K., Rees D.
Title Occupational exposure to ethylene oxide during pregnancy and association with adverse reproductive outcomes
Bibliographic information July 2007, Vol.80, No.7, p.559-565. 19 ref.
Abstract The objective of this study was to investigate the association between exposure to ethylene oxide during pregnancy and adverse reproductive outcomes. The study population consisted of women working during 2004 at hospital sterilising units using ethylene oxide in a South African province. Data on the outcome of the pregnancy were gathered by means of questionnaires. Data on exposure to ethylene oxide during pregnancy was obtained from walk-through surveys, questionnaires and workplace atmosphere measurements. A total of 98 singleton pregnancies were analysed. Measurements of ethylene oxide showed that operators of sterilising units were potentially over-exposed. There was a significantly increased risk of spontaneous abortion (prevalence odds ratio POR 20.8) and pregnancy loss (POR 8.6) for women highly exposed to ethylene oxide compared to low exposed pregnancies. No associations were found between exposure to ethylene oxide and stillbirth.
Descriptors (primary) disinfection of equipment; ethylene oxide; expectant mothers; hospitals; complications of pregnancy
Descriptors (secondary) South Africa; exposure evaluation; determination in air; breathing atmosphere; risk factors; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceSouth Africa
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the reproductive system
Ethers
Ethylene oxide
Health care services