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Document ID (ISN)107148
CIS number 07-1082
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2006
Convention or series no.
Author(s) Chang C.K., Astrakianakis G., Thomas D.B., Seixas N.S., Camp J.E., Ray R.M., Gao D.L., Wernli K.J., Li W., Fitzgibbons E.D., Vaughan T.L., Checkoway H.
Title Risks of biliary tract cancer and occupational exposures among Shanghai women textile workers: A case-cohort study
Bibliographic information Aug. 2006, Vol.49, p.690-698. 42 ref.
Abstract The associations between occupational exposures to textile dusts and chemicals and biliary tract cancer (BTC) were investigated in a cohort of 267,400 women textile workers in Shanghai, China. A nested case-cohort analysis of 162 BTC cases diagnosed during 1989-1998 was conducted with a reference subcohort of 3,188 workers. Exposures to workplace dusts and chemicals were reconstructed by linking complete work history data with a job-exposure matrix. Hazard ratios (HR) and dose-response trends were estimated by Cox proportional hazards modelling modified for case-cohort design. An elevated risk for employment of one year or more in maintenance jobs (HR 2.92) with a significant trend by duration was observed. Excess risk was also found for more than 20 years exposure to metals (HR 2.50).
Descriptors (primary) China; biliary tract diseases; toxic substances; textile industry; cancer; women; respirable dust
Descriptors (secondary) metals; exposure evaluation; job-exposure relation; cohort study; length of exposure; case-control study
Document type D - Periodical articles
Country / State or ProvinceChina; Hong Kong; USA
Subject(s) Textile and clothing industries
Broad subject area(s) Industries and occupations
Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Gastrointestinal diseases