|Document ID (ISN)||107072|
|Convention or series no.
||BUA Report 258
Advisory Committee on Existing Chemicals (BUA)
||S. Hirzel Verlag, Birkenwaldstrasse 44, 70191 Stuttgart, Germany, 2006. xiii, 46p. 81 ref.
||Conclusions of this criteria document which reflects the state of knowledge of July 2005: triethoxy-2,4,4-trimethylpentylsilane is a clear liquid used in the construction industry for the impregnation of concrete. It reacts with water and alcohols. Modes of entry include ingestion and skin absorption. Animal studies show very low toxicity (LD50 at over 2000mg/kg). In rats, target organs of chronic exposure are the forestomach, liver, bladder and kidney. No studies are available on toxic effects to reproduction. In vitro and in vivo studies show the product to be non-mutagenic. Although no experimental data are available, carcinogenicity is considered unlikely. .
||triethoxy-2,4,4-trimethylpentylsilane; Germany; ecotoxicology; toxicology; silanes
||literature survey; irritants; routes of entry; criteria document; concrete; animal experiments; in vitro experiments; skin absorption
||B - Chemical safety information sheets
|Country / State or Province||Germany|
||Toxic and dangerous substances
|Broad subject area(s)