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CISDOC database

Document ID (ISN)107071
CIS number 07-1005
ISBN(s) 978-3-7776-1505-9
Year 2006
Convention or series no. BUA Report 257
Advisory Committee on Existing Chemicals (BUA)
Title 4-Hydroxybutylacrylate
Bibliographic information S. Hirzel Verlag, Birkenwaldstrasse 44, 70191 Stuttgart, Germany, 2006. xiii, 59p. 91 ref.
Abstract Conclusions of this criteria document, which reflects the state of knowledge as of 2005: 4-hydroxybutylacrylate is a high boiling-point, reactive, clear liquid used as a chemical intermediate product in the manufacturing of automobile varnishes. The main modes of entry are through ingestion and skin penetration. Animal studies show low toxicity (LD50 between 500 to 1000mg/kg), with few symptoms appearing below the lethal dose. It is a skin and eye irritant. In vitro studies show the product to be non-mutagenic. Although no experimental data are available, carcinogenicity is considered unlikely.
Descriptors (primary) paint and varnish industry; 4-hydroxybutyl acrylate; ecotoxicology; toxicology; Germany
Descriptors (secondary) literature survey; irritants; routes of entry; criteria document; animal experiments; in vitro experiments; skin absorption
Document type B - Chemical safety information sheets
Country / State or ProvinceGermany
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Pollution control
Chemical industry