ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)107064
CIS number 07-1136
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) Sallmén M., Baird D.D., Hoppin J.A., Blair A., Sandler D.P.
Title Fertility and exposure to solvents among families in the Agricultural Health Study
Bibliographic information July 2006, Vol.63, No.7, p.469-475. Illus. 32 ref.
Abstract The objective of this study was to investigate the impact of solvent exposure on the fertility of couples where the male is a licensed pesticide applicator. The couples were enrolled in a cohort between 1993 and 1997. Exposure to solvents was assessed by means of questionnaires on work tasks. The study was limited to couples (wife aged less than 40 years) with an attempt at pregnancy in the last four years. Twenty eight per cent of the 2112 couples were defined as subfertile. Adjusted subfertility odds ratios (OR) for exposure to solvents were calculated with logistic regression. Female exposure (OR 1.42) and male exposure to solvents (OR 1.21 for monthly exposure and OR 1.40 for daily or weekly exposure) were associated with subfertility. To account for potential dual exposure, variables for parental exposure (either parent exposed or both parents exposed) were also defined. Both were strongly associated with subfertility (OR 1.62 and OR 2.10, respectively).
Descriptors (primary) antifertility effects; pesticide spraying; agriculture; solvents
Descriptors (secondary) USA; sex-linked differences; cohort study; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures