|Document ID (ISN)||106737|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Filon F.L., Boeniger M., Maina G., Adami G., Spinelli P., Damian A.
||Skin absorption of inorganic lead (PbO) and the effect of skin cleansers
||July 2006, Vol.48, No.7, p.692-699. Illus. 40 ref.
||The aim of this study was to investigate the percutaneous penetration of lead oxide (PbO) powder and the effect of two different detergents on the speed of skin decontamination. Franz cells were used to study in vitro PbO skin penetration during a 24h period. The tests were performed without or with decontamination using either a common brand of liquid soap or a new experimental cleanser 30 minutes after the start of exposure. It was confirmed that PbO can pass through the skin with a median penetration of 2.9ng/cm2. The cleaning procedure using the liquid soap significantly increased skin penetration with a median value of 23.6ng/cm2, whereas the new experimental cleanser only marginally increased penetration (7.1ng/cm2). The results indicate that it is necessary to prevent skin contamination from occurring in the first place because a short contact can increase skin penetration even if quickly followed by washing.
||skin contamination; airborne dust; skin cleansers; skin absorption; lead oxide
||D - Periodical articles
|Country / State or Province||Italy|
||Toxic and dangerous substances
|Broad subject area(s)
Lead and compounds