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Document ID (ISN)106735
CIS number 07-645
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) Potula V., Kleinbaum D., Kaye W.
Title Lead exposure and spine bone mineral density
Bibliographic information June 2006, Vol.48, No.6, p.556-564. 58 ref.
Abstract The purpose of this study was to assess changes in spine bone mineral density (BMD) over time in relation to changes in bone and blood lead levels and other risk factors among female former smelter workers. Spine BMD was measured using an X-ray bone densitometer and tibia bone lead content was estimated using an X-ray fluorescence system. Blood lead levels were analyzed using graphite furnace atomic absorption with Zeeman effect background correction. Information about risk factors was obtained through a questionnaire. After controlling for baseline BMD, baseline blood lead measured in 1994 and time since menopause, spine bone density in 2000 decreased with increasing blood lead levels in 2000 in all women, especially if they worked in technical jobs most of the time at the plant.
Descriptors (primary) bone mineral density; smelting plants; lead and compounds
Descriptors (secondary) lead; osteoporosis; menopause; spinal column; determination in bones; confounding factors; women; determination in blood; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Smelting and refining operations
Lead and compounds