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CISDOC database

Document ID (ISN)106523
CIS number 07-581
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) McDuffie H.H., et al.
Title Tumor necrosis factor alpha and pulmonary function in Saskatchewan grain handlers
Bibliographic information May 2006, Vol.48, No.5, p.505-511. 50 ref.
Abstract This study investigated the potential relationship to pulmonary function of factors related to lifestyle (smoking) and inherited susceptibility/resistance (TNF-308 alpha genotype) among grain handlers in the Province of Saskatchewan, Canada. 157 male grain handlers provided occupational and respiratory symptom information, pulmonary function measurements and DNA for genotyping. Findings highlight the complexity of determining which workers will develop acute and chronic adverse pulmonary conditions in response to exposure to grain dust and toxins in cigarette smoke.
Descriptors (primary) smoking; grain dust; respiratory impairment; individual susceptibility; grain and seed processing
Descriptors (secondary) male workers; pulmonary function; DNA; Canada
Document type D - Periodical articles
Country / State or ProvinceCanada; Japan
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Smoking
Diseases of the respiratory system (except for pneumoconiosis & similar)