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Document ID (ISN)106342
CIS number 07-385
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) Wild P.
Title Lung cancer risk and talc not containing asbestiform fibres: A review of epidemiological evidence
Bibliographic information Jan. 2006, Vol.63, No.1, p.4-9. 36 ref.
Abstract This literature survey involved all epidemiological cancer studies mentioning talc as a risk factor. No excess lung cancer mortality was found for talc millers exposed to high levels of talc but without any other potential carcinogen (standardized mortality ratio SMR=0.92, 42 cases) while the mortality of talc miners exposed to quartz and/or radon was in excess (fixed effect, SMR=1.20; random effect, relative risk RR=1.85, 40 cases). Six studies in other industrial settings were identified. All reported increased lung cancer mortality among talc exposed workers but the talc exposure was confounded with other carcinogens and only one study was able to adjust for them. In conclusion, no increased lung cancer mortality was observed among talc millers despite their high exposure experience. In populations in which talc was associated with other potential carcinogens, some lung cancer excesses were observed.
Descriptors (primary) carcinogens; lung cancer; mortality; talc
Descriptors (secondary) literature survey; radon; mining and quarrying; confounding factors; asbestos
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Radon
Diseases of the respiratory system (except for pneumoconiosis & similar)