|Document ID (ISN)||106342|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Lung cancer risk and talc not containing asbestiform fibres: A review of epidemiological evidence
||Jan. 2006, Vol.63, No.1, p.4-9. 36 ref.
||This literature survey involved all epidemiological cancer studies mentioning talc as a risk factor. No excess lung cancer mortality was found for talc millers exposed to high levels of talc but without any other potential carcinogen (standardized mortality ratio SMR=0.92, 42 cases) while the mortality of talc miners exposed to quartz and/or radon was in excess (fixed effect, SMR=1.20; random effect, relative risk RR=1.85, 40 cases). Six studies in other industrial settings were identified. All reported increased lung cancer mortality among talc exposed workers but the talc exposure was confounded with other carcinogens and only one study was able to adjust for them. In conclusion, no increased lung cancer mortality was observed among talc millers despite their high exposure experience. In populations in which talc was associated with other potential carcinogens, some lung cancer excesses were observed.
||carcinogens; lung cancer; mortality; talc
||literature survey; radon; mining and quarrying; confounding factors; asbestos
||D - Periodical articles
|Country / State or Province||France|
Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
Diseases of the respiratory system (except for pneumoconiosis & similar)