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Document ID (ISN)106247
CIS number 07-168
ISSN - Serial title 1077-3525 - International Journal of Occupational and Environmental Health
Year 2006
Convention or series no.
Author(s) Yucra S., Rubio J., Gasco M., Gonzales C., Steenland K., Gonzales G.F.
Title Semen quality and reproductive sex hormone levels in Peruvian pesticide sprayers
Bibliographic information Oct.-Dec. 2006, Vol.12, No.4, p.355-361. Illus. 38 ref.
Internet access [in English]
Abstract To determine the association between occupational pesticide exposure and semen quality among sprayers using organophosphate (OPs) pesticides, 31 pesticide sprayers and 80 men who were not exposed were studied. Semen and blood samples were obtained one day after last pesticide application. Semen samples were analyzed for sperm concentration, percentage of sperm motility, percentage of normal morphology, and fructose and zinc concentrations. Blood samples were analyzed for sex hormones. Pesticide sprayers had significantly reduced age-adjusted seminal volume, percentage of motility, percentage of sperm with normal morphology, serum luteinizing hormone, serum testosterone levels, and seminal zinc concentration (a marker of prostate function), as well as significantly increased time of liquefaction, seminal pH, percentage of immature sperm morphology, and leukocyte concentration. These findings provide further evidence that occupational exposures to OP pesticides adversely affect semen quality and sex hormones.
Descriptors (primary) antifertility effects; crop protection; pesticides; organophosphorus compounds
Descriptors (secondary) spermatogenic disturbances; pesticide spraying; cross-sectional study
Document type D - Periodical articles
Country / State or ProvincePeru; USA
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Agricultural chemicals
Genetic factors in reaction to exposures