ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)106076
CIS number 07-170
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) Lundstr÷m N.G., Englyst V., Gerhardsson L., Jin T., Nordberg G.
Title Lung cancer development in primary smelter workers: A nested case-referent study
Bibliographic information Apr. 2006, Vol.48, No.4, p.376-380. 30 ref.
Abstract The objective of this study was to evaluate the impact of work-related exposure to arsenic and lead versus smoking among lead smelter workers who had developed lung cancer. In a cohort of 3979 lead smelter workers, 46 male subjects had contracted respiratory malignancies. They were compared with 141 age-matched male referents by conditional logistic regression analysis. Cases showed a fourfold higher smoking rate compared with referents. When restricted to smokers, the cumulative air arsenic exposure index, but not the lead exposure indices, was also significantly higher among the cases. It is concluded that cumulative arsenic exposure and smoking were the main risk factors for the development of lung cancer, but not lead exposure.
Descriptors (primary) arsenic; lead; lead industry; lung cancer; smelting plants; smoking
Descriptors (secondary) exposure evaluation; long-term exposure; confounding factors; case-control study
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Industries and occupations
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Smoking
Smelting and refining operations
Arsenic and compounds
Lead and compounds
Inorganic substances