|Document ID (ISN)||106076|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Lundstr÷m N.G., Englyst V., Gerhardsson L., Jin T., Nordberg G.
||Lung cancer development in primary smelter workers: A nested case-referent study
||Apr. 2006, Vol.48, No.4, p.376-380. 30 ref.
||The objective of this study was to evaluate the impact of work-related exposure to arsenic and lead versus smoking among lead smelter workers who had developed lung cancer. In a cohort of 3979 lead smelter workers, 46 male subjects had contracted respiratory malignancies. They were compared with 141 age-matched male referents by conditional logistic regression analysis. Cases showed a fourfold higher smoking rate compared with referents. When restricted to smokers, the cumulative air arsenic exposure index, but not the lead exposure indices, was also significantly higher among the cases. It is concluded that cumulative arsenic exposure and smoking were the main risk factors for the development of lung cancer, but not lead exposure.
||arsenic; lead; lead industry; lung cancer; smelting plants; smoking
||exposure evaluation; long-term exposure; confounding factors; case-control study
||D - Periodical articles
|Country / State or Province||Sweden|
||Metal production and metalworking
|Broad subject area(s)
Industries and occupations
||Diseases of the respiratory system (except for pneumoconiosis & similar)
Smelting and refining operations
Arsenic and compounds
Lead and compounds