ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)105938
CIS number 06-1350
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2005
Convention or series no.
Author(s) Elliott L., Heederick D., Marshall S., Peden D., Loomis D.
Title Incidence of allergy and allergy symptoms among workers exposed to laboratory animals
Bibliographic information Nov. 2005, Vol.62, No.11, p.766-771. Illus. 19 ref.
Abstract In this study on the relation between exposure to laboratory animals and laboratory animal allergy (LAA), data were obtained by questionnaires and serological tests from a cohort of workers exposed to laboratory animals at a pharmaceutical manufacturing company during a 12-year period. Poisson regression was used to model the incidence rate ratios of LAA at different levels of exposure. Higher incidence rate ratios were seen with increasing reported hours carrying out tasks involving working with animal cages or with many animals at one time. The most common symptoms were related to rhinitis rather than to asthma. This study suggests that the risk of LAA increases with duration of exposure to animals and work in animal related tasks. Incidence might be reduced by limiting hours per week of exposure to laboratory animals.
Descriptors (primary) laboratory work; pharmaceutical industry; allergies; experimental animals
Descriptors (secondary) allergens; rhinitis; symptoms; asthma; exposure evaluation; frequency rates; cohort study; long-term study; handling of animals; length of exposure; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceNetherlands; USA
Subject(s) Occupational pathology
Broad subject area(s) Biological hazards
Occupational medicine, epidemiology
Browse category(ies) Allergies
Pharmaceutical industry
Animal hazards